The chemo care cushion is a pillow designed for chemotherapy patients. The pillow provides a barrier between the port and the outside world reducing chance of injury and infection. The cushion allows for users to relax in different positions such as lying on the back stomach or resting the arm on a table or tucked into the body. A plastic insert insures PICC lines during use are kept safe and are unable to be crushed The removable swapable cover insures sanitary conditions. A swappable base allows for different thicknesses insuring a variety of comport levels. A stap ensures during movement the pillow remains with the user so it can be used during activities like driving and playing sports.